Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 6/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.39 |
| ▸ | CDK9 | P50750 | 5/20 | 0.39 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 2/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763071 | 1.00 | ULK1 (0.44) | ULK1FLT3PTK2CHEK1CDK1 | |
| SCHEMBL26920117 | 1.00 | ULK1 (0.44) | ULK1FLT3PTK2CHEK1CDK1 | |
| SCHEMBL26943236 | 0.84 | IKBKB (0.47) | PTK2CDK1CDK2KDRCCNE1 | |
| SCHEMBL26918911 | 0.82 | PTK2 (0.42) | ULK1PTK2CDK1CDK2MAPK3 | |
| SCHEMBL26918921 | 0.82 | PTK2 (0.42) | ULK1PTK2CDK1CDK2MAPK3 | |
| SCHEMBL26943136 | 0.82 | IKBKB (0.45) | CDK1CDK2KDRCCNE1CCNT1 | |
| SCHEMBL25522696 | 0.81 | ULK1 (0.55) | ULK1PTK2CDK1CDK2KDR | |
| SCHEMBL26943302 | 0.80 | IKBKB (0.45) | CDK1CDK2KDRCCNKCDK12 | |
| SCHEMBL31006885 | 0.80 | CCNK (0.56) | CDK2CCNKCDK12CCNE1CCNT1 | |
| SCHEMBL25531573 | 0.80 | CCNK (0.56) | CDK2CCNKCDK12CCNE1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RESEARCH AND DEVELOPMENT CENTRE LTD. (CN) | 2025-01-09 | — | — | US | disclosed |
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-116472270-A | CDK inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-07-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | CDK9, CDKL1, CDK6 | ULK1 1250/4885FLT3 1145/4885PTK2 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.