SCHEMBL2692264

SCHEMBL2692264

CCCCCCCCOC(=O)/C=C/c1cccc(-c2ccccc2)c1C#N

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.45
HDAC8 Q9BY41 2/20 0.44
HCAR2 Q8TDS4 2/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
ALOX5 P09917 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 1/20 0.40
AKR1B10 O60218 2/20 0.40
AKR1B1 P15121 2/20 0.40
TSHR P16473 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39303 0.87 ALDH1A1 (0.48) ALDH1A1KDM4EALOX5SMN1; SMN2HPGD
SCHEMBL39304 0.87 ALDH1A1 (0.48) ALDH1A1KDM4EALOX5SMN1; SMN2HPGD
SCHEMBL156437 0.83 TDP1 (0.50) HDAC8ALDH1A1KDM4EALOX5TSHR
SCHEMBL288562 0.83 TDP1 (0.50) HDAC8ALDH1A1KDM4EALOX5TSHR
SCHEMBL5494926 0.82 PTGER1 (0.37) HDAC8HCAR2ALDH1A1KDM4EALOX5
SCHEMBL28629258 0.81 APP (0.47) APPHDAC8HCAR2ALDH1A1KDM4E
SCHEMBL990905 0.81 ALOX5 (0.41) ALDH1A1KDM4EALOX5AKR1B10AKR1B1
SCHEMBL31279789 0.81 APP (0.51) APPHCAR2ALDH1A1KDM4ESMN1; SMN2
SCHEMBL5960780 0.80 APP (0.41) APPALDH1A1KDM4EALOX5LMNA
SCHEMBL15665995 0.79 APP (0.47) APPHDAC8HCAR2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12414909-B2 Polysaccharide-based gelled foam URGO RECHERCHE INNOVATION ET DEVELOPPEMENT (FR) 2025-09-16 US disclosed
US-20220370329-A1 POLYSACCHARIDE-BASED GELLED FOAM URGO RECHERCHE INNOVATION ET DEVELOPPEMENT (FR) 2022-11-24 US disclosed
EP-3544573-A1 FILM-FORMING COMPOSITION Urgo Recherche Innovation et Développement (FR) 2019-10-02 EP disclosed
US-9642790-B2 Aqueous dispersion of polymer particles, film-forming composition containing same and uses thereof VIVATECH (FR) 2017-05-09 US disclosed
US-9198998-B2 Composition containing a cellulose, a vegetable oil and a volatile solvent, and use thereof as a dressing LABORATORIES URGO (FR) 2015-12-01 US disclosed
US-20150174042-A1 AQUEOUS DISPERSION OF POLYMER PARTICLES, FILM-FORMING COMPOSITION CONTAINING SAME AND USES THEREOF VIVATECH (FR) 2015-06-25 US disclosed
US-20140154188-A1 COMPOSITION CONTAINING A CELLULOSE, A VEGETABLE OIL AND A VOLATILE SOLVENT, AND USE THREOF AS A DRESSING LABORATOIRES URGO (FR) 2014-06-05 US disclosed
US-8741347-B2 Method for forming cyclodextrin polymer and lipophilic compound emulsions, resulting emulsions, and compositions including said emulsions Centre National de la Recherche Scientifique—CNRS (FR) 2014-06-03 US disclosed
US-20140128468-A1 TOPICAL FILM-FORMING COMPOSITION, AND USE THEREOF FOR TREATING MYCOSES LABORATOIRES URGO (FR) 2014-05-08 US disclosed
US-20120107252-A1 METHOD FOR FORMING CYCLODEXTRIN POLYMER AND LIPOPHILIC COMPOUND EMULSIONS, RESULTING EMULSIONS, AND COMPOSITIONS INCLUDING SAID EMULSIONS UNIVERSITE PARIS-SUD 11 (FR) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120107252-A1 METHOD FOR FORMING CYCLODEXTRIN POLYMER AND LIPOPHILIC COMPOUND EMULSIONS, RESULTING EMULSIONS, AND COMPOSITIONS INCLUDING SAID EMULSIONS LIPA, NOTUM, CEL APP 133/4885HDAC8 3229/4885HCAR2 2665/4885
US-20140128468-A1 TOPICAL FILM-FORMING COMPOSITION, AND USE THEREOF FOR TREATING MYCOSES CUTA, NACA, DPM1 APP 957/4885HDAC8 2630/4885HCAR2 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.