Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611795 | 1.00 | ESR2 (0.44) | ESR2MGLLAPPIDH1HSD11B1 | |
| SCHEMBL15028921 | 0.92 | MGLL (0.40) | ESR2MGLLAPPIDH1PTGS1 | |
| SCHEMBL13499049 | 0.85 | APP (0.41) | MGLLAPPIDH1PTGS1PTGS2 | |
| SCHEMBL21872033 | 0.83 | APP (0.43) | MGLLAPPPTGS1PTGS2PDK2 | |
| SCHEMBL21872202 | 0.83 | APP (0.43) | MGLLAPPPTGS1PTGS2PDK2 | |
| SCHEMBL21872092 | 0.83 | APP (0.43) | MGLLAPPPTGS1PTGS2PDK2 | |
| SCHEMBL30910925 | 0.81 | PDE2A (0.38) | ESR2MGLLAPPIDH1QDPR | |
| SCHEMBL18097789 | 0.81 | PDE2A (0.38) | ESR2MGLLAPPIDH1QDPR | |
| SCHEMBL14817246 | 0.79 | ESR2 (0.53) | ESR2QDPRPDK2 | |
| SCHEMBL21831890 | 0.78 | IDH1 (0.37) | ESR2MGLLAPPIDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426465-B | Method for carrying out photo-delay reaction on alcohol hydroxyl donor and active hydrogen donor | 江苏和成新材料有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | JIANGSU HECHENG ADVANCED MATERIALS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | JIANGSU HECHENG ADVANCED MATERIALS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | JIANGSU HECHENG ADVANCED MATERIALS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| CN-114426466-B | Method for carrying out photo-delay reaction on alcohol hydroxyl donor and active hydrogen donor | 江苏和成新材料有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022088244-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | 江苏和成新材料有限公司 | 2022-05-05 | — | — | WO | disclosed |
| CN-114426466-A | Method for carrying out mitsunobu reaction on alcoholic hydroxyl donor and active hydrogen donor | 江苏和成新材料有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-114426465-A | Method for carrying out mitsunobu reaction on alcoholic hydroxyl donor and active hydrogen donor | 江苏和成新材料有限公司 | 2022-05-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399281-A1 | METHOD FOR PERFORMING MITSUNOBU REACTION BETWEEN ALCOHOLIC HYDROXYL GROUP DONOR AND ACTIVE HYDROGEN DONOR | ADH5, ADH1C, ADH1A | ESR2 3431/4885MGLL 302/4885APP 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.