Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26932111 | 0.89 | L3MBTL3 (0.41) | POLBMYCKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17893671 | 0.88 | PRKDC (0.53) | POLBLGMNMYCKMT2AALDH1A1 | |
| SCHEMBL17893686 | 0.86 | ALDH1A1 (0.47) | POLBLGMNKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17893773 | 0.86 | NPC1 (0.44) | POLBLGMNMAPK8MAPK10KMT2A | |
| SCHEMBL15238295 | 0.86 | LGMN (0.46) | POLBLGMNMAPK8MAPK10KMT2A | |
| SCHEMBL31568638 | 0.84 | LGMN (0.41) | POLBLGMNMAPK8MAPK10KMT2A | |
| SCHEMBL15547618 | 0.83 | PRKDC (0.56) | KMT2AALDH1A1SMN1; SMN2PRKDCMAPT | |
| SCHEMBL15238296 | 0.83 | ALDH1A1 (0.57) | POLBLGMNKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31568634 | 0.82 | ALDH1A1 (0.40) | POLBLGMNMAPK8MAPK10KMT2A | |
| SCHEMBL16056102 | 0.82 | ALDH1A1 (0.49) | POLBLGMNKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |