Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LGMN | Q99538 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702599 | 0.83 | SIRT6 (0.35) | ALDH1A1KMT2ASMN1; SMN2SIRT6PRKDC | |
| SCHEMBL26931936 | 0.82 | POLB (0.44) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 | |
| SCHEMBL17893671 | 0.82 | PRKDC (0.53) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 | |
| SCHEMBL17893686 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 | |
| SCHEMBL17893773 | 0.81 | NPC1 (0.44) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 | |
| SCHEMBL31568638 | 0.80 | LGMN (0.41) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 | |
| SCHEMBL30694298 | 0.79 | GPR183 (0.40) | — | |
| SCHEMBL29148098 | 0.79 | GPR183 (0.40) | — | |
| SCHEMBL16055437 | 0.78 | HIF1A (0.41) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 | |
| SCHEMBL16056102 | 0.78 | ALDH1A1 (0.49) | ALDH1A1POLBLGMNKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4541795-A1 | AROMATIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PREPARATION OF ESTROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2025-04-23 | — | — | EP | disclosed |