Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30693081 | 1.00 | CYP2A6 (0.47) | CYP2A6MPOHSD11B1EGLN2ABCC9 | |
| SCHEMBL2695236 | 0.85 | MEN1 (0.43) | CYP2A6MPOHSD11B1ABCC9ABCC8 | |
| SCHEMBL1642300 | 0.84 | FFAR1 (0.48) | CYP2A6EGLN2ABCC9ABCC8KCNJ11 | |
| SCHEMBL15018450 | 0.84 | MPO (0.43) | MPOHSD11B1EGLN2FFAR1FFAR4 | |
| SCHEMBL3035956 | 0.82 | MAPT (0.35) | CYP2A6FFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL18615344 | 0.81 | PGR (0.50) | CYP2A6SLC6A4KCNH2PGRGAA | |
| SCHEMBL13824727 | 0.81 | CYP2A6 (0.52) | CYP2A6EGLN2ABCC9ABCC8KCNJ11 | |
| SCHEMBL26948215 | 0.80 | SLC6A4 (0.40) | CYP2A6MPOHSD11B1ABCC9ABCC8 | |
| SCHEMBL18493859 | 0.80 | LOXL2 (0.47) | MPOHSD11B1EGLN2SLC6A4SLC6A3 | |
| SCHEMBL411021 | 0.80 | MPO (0.43) | CYP2A6MPOHSD11B1EGLN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118315670-A | Electrolyte additive and application thereof, single-particle graphite negative electrode electrolyte and application thereof | 国网湖南省电力有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-108623496-B | Preparation method of 3-ethyl-4-fluorobenzonitrile | 上海特化医药科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-108623496-A | The preparation method of 3- ethyl -4- fluorobenzonitriles | 上海特化医药科技有限公司 | 2018-10-09 | — | — | CN | claimed |
| US-20250353843-A1 | ANALOGUES OF AZABICYCLIC COMPOUNDS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2025-11-20 | — | — | US | disclosed |
| EP-4538257-A1 | ANALOGUES OF AZABICYCLIC COMPOUNDS | Taiho Pharmaceutical Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| CN-119365442-A | Azabicyclo compounds analogues of the same | 大鹏药品工业株式会社 | 2025-01-24 | — | — | CN | disclosed |
| CN-118315670-A | Electrolyte additive and application thereof, single-particle graphite negative electrode electrolyte and application thereof | 国网湖南省电力有限公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2023238930-A1 | ANALOGUES OF AZABICYCLIC COMPOUNDS | 大鵬薬品工業株式会社 | 2023-12-14 | — | — | WO | disclosed |
| WO-2023240253-A2 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| CN-115960100-B | Synthesis method of Pi Mite xib drug for treating gastrointestinal stromal tumor | 北京康立生医药技术开发有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-115960100-A | Synthetic method of drug Pi Mite Xibu for treating gastrointestinal stromal tumor | 北京康立生医药技术开发有限公司 | 2023-04-14 | — | — | CN | disclosed |
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | disclosed |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-22 | — | — | US | disclosed |
| US-20080027050-A1 | Heterocyclic Amide Compound and Use Thereof as an Mmp-13 Inhibitor(Amended Ex Officio) | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-31 | — | — | US | disclosed |
| WO-2007145570-A1 | AMINO-IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA | ASTRAZENECA AB (SE) | 2007-12-21 | — | — | WO | disclosed |
| US-7297695-B2 | Pyrrolotriazine compounds as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | PFIZER INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1740551-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | Takeda Pharmaceutical Company Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105760-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | CYP2A6 81/4885MPO 1879/4885HSD11B1 2392/4885 |
| US-20080027050-A1 | Heterocyclic Amide Compound and Use Thereof as an Mmp-13 Inhibitor(Amended Ex Officio) | MMP13, HDAC11, HDAC1 | CYP2A6 171/4885MPO 426/4885HSD11B1 46/4885 |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | CYP2A6 81/4885MPO 1879/4885HSD11B1 2392/4885 |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | CYP2A6 81/4885MPO 1879/4885HSD11B1 2392/4885 |
| US-20070082908-A1 | Bicycle pyrazole derivative | DPP4, DPP7, DPP3 | CYP2A6 124/4885MPO 1294/4885HSD11B1 261/4885 |
| US-20250353843-A1 | ANALOGUES OF AZABICYCLIC COMPOUNDS | API5, AZI2, CYP4B1 | CYP2A6 1204/4885MPO 3029/4885HSD11B1 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.