SCHEMBL2693344

SCHEMBL2693344

CC(C)(C)OC(=O)NC1CCN(CC(=O)O)CC1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.54
CTSK P43235 2/20 0.52
BTK Q06187 1/20 0.49
USP14 P54578 1/20 0.47
DRD2 P14416 4/20 0.46
CCR5 P51681 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CKS1B P61024 1/20 0.45
SKP1 P63208 1/20 0.45
SKP2 Q13309 1/20 0.45
CYP2C9 P11712 1/20 0.44
HSD11B1 P28845 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
EPHX1 P07099 2/20 0.43
KDM1A O60341 1/20 0.43
MAOB P27338 1/20 0.43
DRD3 P35462 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5847911 0.91 CTSK (0.57) KCNA3CTSKBTKDRD2CCR5
SCHEMBL8256718 0.91 CTSK (0.57) KCNA3CTSKBTKDRD2CCR5
SCHEMBL10006308 0.91 CTSK (0.57) KCNA3CTSKBTKDRD2CCR5
SCHEMBL7586943 0.87 CTSK (0.51) KCNA3CTSKBTKUSP14DRD2
SCHEMBL620491 0.85 CTSK (0.50) KCNA3CTSKBTKUSP14DRD2
SCHEMBL26661838 0.85 KCNA3 (0.61) KCNA3CTSKBTKDRD2CCR5
SCHEMBL15373110 0.85 KCNA3 (0.52) KCNA3CTSKBTKUSP14DRD2
SCHEMBL18551557 0.85 BTK (0.45) KCNA3CTSKBTKUSP14DRD2
SCHEMBL22399970 0.85 BTK (0.45) KCNA3CTSKBTKUSP14DRD2
SCHEMBL18551138 0.85 BTK (0.45) KCNA3CTSKBTKUSP14DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US disclosed
EP-4622966-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-01 EP disclosed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 EP disclosed
EP-4405359-A2 MDM2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2024-07-31 EP disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
WO-2024112612-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-05-30 WO disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 WO disclosed
US-11833208-B2 PLK1 selective degradation inducing compound UPPTHERA, INC. (KR) 2023-12-05 US disclosed
US-11833208-B2 PLK1 selective degradation inducing compound UPPTHERA, INC. (KR) 2023-12-05 US disclosed
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND UPPTHERA (KR) 2023-11-23 US disclosed
US-20040087622-A1 Benzamide derivative and medicament containing the same KATO HIDEO (JP) 2004-05-06 US disclosed
US-6638951-B1 Medicament has excellent enhancing action on gastrointestinal tract motility, and is orally available with reduced side effects, the agent for therapeutic treatment of digestive diseases, an agent for improving function of gastrointestinal HOKURIKU SEIYAKU CO., LTD. (JP) 2003-10-28 US disclosed
US-6518423-B1 These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and EISAI CO., LTD. (JP) 2003-02-11 US disclosed
EP-1149832-B1 BENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME HOKURIKU PHARMACEUTICAL (JP) 2003-01-02 EP disclosed
US-20020115715-A1 Amine and amide derivatives as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders DAX SCOTT L (US) 2002-08-22 US disclosed
EP-1202986-A1 AMINE AND AMIDE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR USEFUL IN THE TREATMENT OF OBESITY AND OTHER DISORDERS Ortho-McNeil Pharmaceutical, Inc. (US) 2002-05-08 EP disclosed
US-6380224-B1 FOR THERAPY OF EATING DISORDERS, OBESITY, BULIMIA NERVOSA, DIABETES, MEMORY LOSS, EPILEPTIC SEIZURES, MIGRAINE, SLEEP DISTURBANCES, PAIN, SEXUAL/REPRODUCTIVE DISORDERS, DEPRESSION AND ANXIETY ORTHO-MCNEIL PHARMACEUTICAL, INC. 2002-04-30 US disclosed
EP-1149832-A1 BENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME HOKURIKU SEIYAKU CO., LTD. (JP) 2001-10-31 EP disclosed
WO-2001009120-A1 AMINE AND AMIDE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR USEFUL IN THE TREATMENT OF OBESITY AND OTHER DISORDERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-02-08 WO disclosed
EP-0934941-A1 BENZOPIPERIDINE DERIVATIVES Eisai Co., Ltd. (JP) 1999-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087622-A1 Benzamide derivative and medicament containing the same SLC10A2, FABP2, HDAC6 KCNA3 553/4885CTSK 713/4885BTK 3162/4885
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND PLK1, BUB1B, BUB1 KCNA3 3663/4885CTSK 1058/4885BTK 2004/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR KCNA3 3529/4885CTSK 1492/4885BTK 1512/4885
US-20020115715-A1 Amine and amide derivatives as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders NPY5R, NPY1R, NPY2R KCNA3 1535/4885CTSK 3078/4885BTK 1599/4885
US-11833208-B2 PLK1 selective degradation inducing compound PLK1, BUB1B, BUB1 KCNA3 3663/4885CTSK 1058/4885BTK 2004/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R KCNA3 3969/4885CTSK 798/4885BTK 1959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.