Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47861 | 0.86 | TSHR (0.56) | TSHRCASP1APPPTGS1ACHE | |
| SCHEMBL1513516 | 0.83 | HSD17B1 (0.60) | ERCC1ERCC4TNKS2HSD17B1HSD17B2 | |
| SCHEMBL22107622 | 0.83 | ERN1 (0.51) | TSHRCASP1APPPTGS1ACHE | |
| SCHEMBL1007614 | 0.82 | MCL1 (0.52) | TSHRCASP1APPPTGS1ACHE | |
| SCHEMBL26936683 | 0.82 | ESR2 (0.60) | CASP1TNKS2APPACHEHSD17B1 | |
| SCHEMBL129788 | 0.81 | — | — | |
| SCHEMBL30755529 | 0.81 | — | — | |
| SCHEMBL1005170 | 0.80 | ALOX5 (0.64) | TSHRCASP1APPHSD17B1HSD17B2 | |
| SCHEMBL14295102 | 0.79 | MCL1 (0.57) | TSHRCASP1APPPTGS1ACHE | |
| SCHEMBL12387990 | 0.79 | APP (0.70) | TSHRCASP1APPPTGS1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |