SCHEMBL269377

SCHEMBL269377

COC(=O)c1ccc(OCN)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.72
RAB9A P51151 5/20 0.64
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
LOXL2 Q9Y4K0 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.58
NPC1 O15118 4/20 0.58
STS P08842 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
TDP1 Q9NUW8 2/20 0.54
LMNA P02545 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
GAA P10253 1/20 0.54
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
POLB P06746 1/20 0.51
BLM P54132 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443043 0.85 MAPT (0.79) MAPTRAB9ACA1CA2LOXL2
SCHEMBL1951546 0.84 MAPT (1.00) MAPTRAB9ACA1CA2LOXL2
SCHEMBL8683825 0.84 MAPT (0.77) MAPTRAB9ACA1CA2LOXL2
Hydrochloric Acid SCHEMBL442778 0.84 MAPT (0.77) MAPTRAB9ACA1CA2LOXL2
SCHEMBL21740970 0.83 MAPT (0.70) MAPTRAB9ACA1CA2LOXL2
SCHEMBL2469151 0.82 MAPT (0.89) MAPTRAB9ACA1CA2SMN1; SMN2
SCHEMBL10295156 0.82 MAPT (0.75) MAPTRAB9ACA1CA2LOXL2
SCHEMBL204175 0.82 MAPT (0.75) MAPTRAB9ACA1CA2SMN1; SMN2
Hydrochloric Acid SCHEMBL6982145 0.82 MAPT (0.74) MAPTRAB9ACA1CA2LOXL2
SCHEMBL6538707 0.81 MAPT (0.68) MAPTRAB9ACA1CA2LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573453-B Selective of Carboxylic ester cleavage process 荆楚理工学院 2024-12-03 CN claimed
US-20230234918-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2023-07-27 US claimed
EP-4178942-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER Council Of Scientific & Industrial Research (IN) 2023-05-17 EP claimed
CN-115956066-A Automatic diazomethane generator, reactor and solid phase quenching agent 科学与工业研究委员会 2023-04-11 CN claimed
WO-2022044038-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-03-03 WO claimed
US-4444567-A ALKOXY BENZALDEHYDES, ALKOXY BENZOATES PHILLIPS PETROLEUM COMPANY (US) 1984-04-24 US claimed
EP-4737508-A1 CHEMICAL RECYCLING METHOD FOR MIXED WASTE POLYMERS Korea Research Institute of Chemical Technology (KR) 2026-05-06 EP disclosed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US disclosed
WO-2025029018-A1 CHEMICAL RECYCLING METHOD FOR MIXED WASTE POLYMERS 한국화학연구원 2025-02-06 WO disclosed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP disclosed
CN-114573453-B Selective of Carboxylic ester cleavage process 荆楚理工学院 2024-12-03 CN disclosed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 WO disclosed
CN-112876482-B Polysubstituted heterocyclic derivative, preparation method and medical application thereof 中国药科大学 2023-07-28 CN disclosed
US-5698720-A INTERMEDIATES FOR TESTOSTERONE 5-ALPHA-REDUCTASE INHIBITORS SANKYO COMPANY, LIMITED (JP) 1997-12-16 US disclosed
EP-0567271-B1 Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses SANKYO CO (JP) 1997-07-02 EP disclosed
EP-0725074-A2 Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives SANKYO COMPANY LIMITED (JP) 1996-08-07 EP disclosed
US-5536714-A Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses SANKYO COMPANY, LIMITED (JP) 1996-07-16 US disclosed
US-4444567-A ALKOXY BENZALDEHYDES, ALKOXY BENZOATES PHILLIPS PETROLEUM COMPANY (US) 1984-04-24 US disclosed
US-4249015-A Preparation of organic acids and/or esters SHELL OIL COMPANY (US) 1981-02-03 US disclosed
US-4212867-A FOR AGRICULTURAL USE PHILAGRO (FR) 1980-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 MAPT 3110/4885RAB9A 4242/4885CA1 2951/4885
US-20230234918-A1 AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER FTO, MNAT1, ALKBH2 MAPT 2101/4885RAB9A 4756/4885CA1 471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.