Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20411228 | 0.79 | KDM5B (0.32) | KDM5BTHRBTGFBR1MAPK14 | |
| SCHEMBL25632354 | 0.77 | KDM5B (0.31) | KDM5B | |
| SCHEMBL15912316 | 0.76 | KDM5B (0.34) | KDM5B | |
| SCHEMBL13075463 | 0.75 | THRB (0.35) | THRBTGFBR1MAPK14 | |
| SCHEMBL25985962 | 0.75 | KDM5B (0.33) | KDM5B | |
| SCHEMBL22421091 | 0.74 | MAP3K14 (0.31) | — | |
| SCHEMBL20993428 | 0.74 | KDM5B (0.33) | KDM5B | |
| SCHEMBL27336699 | 0.73 | LIPE (0.31) | — | |
| SCHEMBL19099498 | 0.73 | PDE5A (0.32) | KDM5BTHRBTGFBR1MAPK14 | |
| SCHEMBL24744542 | 0.72 | THRB (0.33) | THRBTGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | JAPAN TOBACCO INC. (JP) | 2023-12-14 | — | — | US | disclosed |
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | JAPAN TOBACCO INC. (JP) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | NLRP3, NLRP1, NOD1 | KDM5B 3998/4885THRB 3819/4885TGFBR1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.