Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628436 | 0.81 | ROCK2 (0.60) | NR1H4HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL18715505 | 0.80 | ROCK1 (0.59) | MMP13RAB9AROCK2ROCK1CYP3A4 | |
| SCHEMBL2288184 | 0.79 | NR1H4 (0.61) | NR1H4MAPTMLYCDLMNARAB9A | |
| SCHEMBL13001971 | 0.75 | HDAC6 (0.66) | NR1H4HDAC6LMNARAB9AHDAC1 | |
| SCHEMBL694147 | 0.74 | CYP1A2 (0.54) | MAPTMMP13LMNARAB9AROCK2 | |
| SCHEMBL13670025 | 0.72 | ALDH1A1 (0.60) | MAPTLMNASENP1CYP3A4CYP2C9 | |
| SCHEMBL13491410 | 0.72 | PLK1 (0.60) | MAPTHDAC6LMNARAB9AHDAC1 | |
| SCHEMBL27621163 | 0.71 | PTPN1 (0.48) | MAPTRAB9AROCK2ROCK1ALDH1A1 | |
| SCHEMBL15339189 | 0.70 | NR1H4 (0.56) | NR1H4MLYCDMMP13HDAC6LMNA | |
| SCHEMBL5913323 | 0.70 | L3MBTL1 (0.45) | NR1H4MAPTMLYCDHDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239906-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | WO | disclosed |