Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121227 | 0.78 | ALDH1A1 (0.53) | BRD4ALDH1A1HTTGAABCHE | |
| SCHEMBL26945697 | 0.77 | ALDH1A1 (0.34) | BRD4ALDH1A1HTTGAABCHE | |
| SCHEMBL19504917 | 0.76 | ADORA2A (0.38) | ALDH1A1HTTGAA | |
| SCHEMBL6920216 | 0.75 | APAF1 (0.50) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ALDH1A1 | |
| SCHEMBL26940067 | 0.73 | ATM (0.43) | ALDH1A1HTTATM | |
| SCHEMBL11629541 | 0.70 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3CYP1A2 | |
| SCHEMBL1234455 | 0.68 | BRD4 (0.35) | CSNK2A2CSNK2BCSNK2A1CSNK2A3BRD4 | |
| SCHEMBL13784464 | 0.67 | — | — | |
| SCHEMBL12479057 | 0.67 | GAA (0.56) | BRD4ALDH1A1HTTGAABCHE | |
| SCHEMBL1075036 | 0.67 | CYP1A2 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240138-A1 | INDAZOLE CONTAINING MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |