Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23403490 | 0.83 | ADORA2A (0.37) | ALDH1A1APAF1GLS | |
| SCHEMBL12121227 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTBRD4GAACYP1A2 | |
| SCHEMBL23402270 | 0.79 | NR1H3 (0.37) | ALDH1A1GAACYP1A2ATM | |
| SCHEMBL23399529 | 0.77 | LMNA (0.38) | ALDH1A1HTTAPAF1 | |
| SCHEMBL26944155 | 0.77 | CSNK2A2 (0.35) | ALDH1A1HTTBRD4GAACYP1A2 | |
| SCHEMBL23399089 | 0.72 | APAF1 (0.44) | ALDH1A1APAF1 | |
| SCHEMBL12124398 | 0.72 | KDM4E (0.38) | ALDH1A1HTTGAABCHE | |
| SCHEMBL26940067 | 0.71 | ATM (0.43) | ALDH1A1HTTATM | |
| SCHEMBL6920216 | 0.68 | APAF1 (0.50) | ALDH1A1HTTGAACYP1A2ATM | |
| SCHEMBL12479057 | 0.68 | GAA (0.56) | ALDH1A1HTTBRD4GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240138-A1 | INDAZOLE CONTAINING MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |