Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26944345 | 0.82 | KMT2A (0.46) | HRH3TLR7TLR9TLR8HRH1 | |
| SCHEMBL4554100 | 0.82 | CHRNB2 (0.56) | HRH3CHRNB2CHRNA4 | |
| SCHEMBL12049097 | 0.82 | CHRNB2 (0.51) | HRH3HRH1MEN1KMT2AATM | |
| SCHEMBL16345634 | 0.81 | TRPV6 (0.48) | HRH3AXLFLT3TYRO3MERTK | |
| SCHEMBL3508945 | 0.81 | KMT2A (0.56) | HRH3MEN1KMT2AATMCHRNB2 | |
| SCHEMBL31003316 | 0.81 | IDH1 (0.49) | HRH3TLR7BRD4AXLFLT3 | |
| SCHEMBL12334539 | 0.80 | HRH3 (0.59) | HRH3MEN1KMT2ACYP2D6CHRNB2 | |
| SCHEMBL21552456 | 0.80 | HPGD (0.59) | MEN1KMT2ACYP2D6 | |
| SCHEMBL1666554 | 0.79 | ALDH1A1 (0.61) | HRH1MEN1KMT2AATM | |
| SCHEMBL14308131 | 0.79 | LMNA (0.54) | HRH3MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235925-A1 | COMPOUNDS WITH MERTK ACTIVITY | MONASH UNIVERSITY (AU) | 2023-12-14 | — | — | WO | disclosed |