⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676153 | 0.84 | — | — | |
| SCHEMBL5533465 | 0.82 | ALDH1A1 (0.72) | — | |
| SCHEMBL7692370 | 0.80 | ALDH1A1 (0.77) | — | |
| SCHEMBL4679040 | 0.80 | — | — | |
| SCHEMBL1416682 | 0.78 | — | — | |
| SCHEMBL10667282 | 0.77 | FAAH (0.56) | — | |
| SCHEMBL5830059 | 0.77 | ALDH1A1 (0.83) | — | |
| SCHEMBL3074569 | 0.77 | — | — | |
| SCHEMBL11127833 | 0.77 | ALDH1A1 (0.94) | — | |
| SCHEMBL1042080 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179109-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. | 2010-07-15 | — | — | US | claimed |
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | claimed |
| CN-117916309-A | Acrylic rubber composition | 株式会社大阪曹达 | 2024-04-19 | — | — | CN | disclosed |
| EP-1963403-B1 | SILICON-CONTAINING MONOMERS END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | BAUSCH & LOMB (US) | 2012-08-15 | — | — | EP | disclosed |
| US-8133512-B2 | Drug delivery systems based on catonic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-8133511-B2 | Drug delivery system based on cationic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-7960447-B2 | Cationic end-capped siloxane prepolymer for reduced cross-link density | BAUSCH & LOMB INCORPORATED (US) | 2011-06-14 | — | — | US | disclosed |
| US-7759408-B2 | Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2010-07-20 | — | — | US | disclosed |
| EP-2121450-A1 | PACKAGING SYSTEM FOR CONTACT LENSES | Bausch & Lomb Incorporated (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20090274744-A1 | Drug delivery system based on cationic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090274745-A1 | Drug delivery systems based on catonic siloxanyl macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
| EP-2004729-A1 | CATIONIC END-CAPPED SILOXANE PREPOLYMER FOR REDUCED CROSS-LINK DENSITY | Bausch & Lomb Incorporated (US) | 2008-12-24 | — | — | EP | disclosed |
| EP-1963403-A2 | SILICON-CONTAINING MONOMERS END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2008079716-A1 | PACKAGING SYSTEM FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080152540-A1 | PACKAGING SOLUTIONS | BAUSCH & LOMB INCORPORATED (US) | 2008-06-26 | — | — | US | disclosed |
| US-20080075780-A1 | Drug delivery systems based on degradible cationic siloxanyl macromonomers | SANTARUS, INC. | 2008-03-27 | — | — | US | disclosed |
| WO-2007121084-A1 | CATIONIC END-CAPPED SILOXANE PREPOLYMER FOR REDUCED CROSS-LINK DENSITY | BAUCH & LOMB INCORPORATED (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070242215-A1 | Cationic end-capped siloxane prepolymer for reduced cross-link density | BAUSCH & LOMB INCORPORATED | 2007-10-18 | — | — | US | disclosed |
| WO-2007078661-A2 | SILICON-CONTAINING MONOMERS END-CAPPED WITH POLYMERIZABLE CATIONIC HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070142584-A1 | Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups | LABORATOIRE CHAUVIN S.A.S. (FR) | 2007-06-21 | — | — | US | disclosed |