SCHEMBL26961007

SCHEMBL26961007

CC(C)(C)OC(=O)N1CC(S(=N)(=O)c2ccccc2)C1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RORC P51449 3/20 0.47
GPR119 Q8TDV5 4/20 0.47
STS P08842 2/20 0.46
NAMPT P43490 1/20 0.45
USP30 Q70CQ3 2/20 0.45
TGFBR1 P36897 1/20 0.44
NR1H2 P55055 3/20 0.43
NR1H3 Q13133 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17680273 0.88 GPR119 (0.45) RORCGPR119STSUSP30NR1H2
SCHEMBL25326710 0.81 GPR119 (0.48) RORCGPR119STSNAMPTKDM4E
SCHEMBL2412974 0.80 RORC (0.46) RORCGPR119STSNAMPTUSP30
SCHEMBL19707185 0.79 GPR119 (0.47) GPR119STSNAMPTTGFBR1NR1H2
SCHEMBL26960975 0.79 KDM4E (0.42) RORCGPR119STSNAMPTUSP30
SCHEMBL19640875 0.78 HSD11B1 (0.52) RORCGPR119STSNAMPTUSP30
SCHEMBL26966945 0.78 GPR119 (0.47) GPR119STSNAMPTTGFBR1
SCHEMBL25255059 0.77 RORC (0.50) RORCGPR119STSNAMPTNR1H2
SCHEMBL13947675 0.77 GPR119 (0.59) GPR119STSNAMPTTGFBR1KDM4E
SCHEMBL23113061 0.76 RORC (0.44) RORCGPR119STSNAMPTUSP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399302-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-SUBSTITUTED SULFUR(VI) COMPOUNDS NATIONAL INSTITUTES OF HEALTH 2023-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399302-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-SUBSTITUTED SULFUR(VI) COMPOUNDS TST, TYR, STS RORC 1600/4885GPR119 4716/4885STS 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.