SCHEMBL26964488

SCHEMBL26964488

COc1ccc(-n2sc3ncccc3c2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 15/20 1.00
EP300 Q09472 2/20 0.70
CREBBP Q92793 2/20 0.70
KAT2A Q92830 2/20 0.70
MMP10 P09238 2/20 0.69
G6PD P11413 1/20 0.61
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29798990 1.00 KAT2B (1.00) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL29798968 0.83 KAT2B (1.00) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL26964521 0.83 KAT2B (1.00) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL1902882 0.83 KAT2B (0.70) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL29530268 0.83 KAT2B (0.70) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL29711802 0.82 KAT2B (1.00) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL20771520 0.82 KAT2B (1.00) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL20350785 0.82 KAT2B (1.00) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL17515280 0.79 KAT2B (0.76) KAT2BEP300CREBBPKAT2AMMP10
SCHEMBL1897990 0.76 G6PD (1.00) KAT2BEP300KAT2AG6PDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018180-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2024-01-18 US claimed
EP-4293035-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2023-12-20 EP claimed
US-20240018180-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2024-01-18 US disclosed
US-20240018180-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2024-01-18 US disclosed
EP-4293035-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2023-12-20 EP disclosed
WO-2022172994-A1 OLIGONUCLEOTIDE PRODUCTION METHOD 味の素株式会社 2022-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018180-A1 OLIGONUCLEOTIDE PRODUCTION METHOD RNGTT, NOX4, POLRMT KAT2B 1902/4885EP300 3591/4885CREBBP 1940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.