SCHEMBL26965639

SCHEMBL26965639

CN(C)CCc1c[nH]c2cccc(OS)c12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.77
HTR2A P28223 11/20 0.67
HTR2C P28335 7/20 0.67
HTR2B P41595 7/20 0.67
HTR1A P08908 5/20 0.67
DRD1 P21728 1/20 0.63
HTR1D P28221 1/20 0.63
HTR1B P28222 1/20 0.63
HTR1E P28566 1/20 0.63
ADORA2A P29274 1/20 0.63
ADORA2B P29275 1/20 0.63
HTR7 P34969 1/20 0.63
DRD3 P35462 1/20 0.63
HTR5A P47898 1/20 0.63
SLC6A4 P31645 1/20 0.53
HTR1F P30939 1/20 0.50
SLC6A2 P23975 1/20 0.47
MPO P05164 1/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993252 0.87 HTR6 (1.00) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL29758535 0.87 HTR6 (1.00) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL19235737 0.87 HTR6 (1.00) HTR6HTR2AHTR2CHTR2BHTR1A
Hydrochloric Acid SCHEMBL4208783 0.86 HTR6 (0.97) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL24723621 0.83 HTR6 (0.73) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL30681600 0.83 HTR6 (0.73) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL29992491 0.83 HTR6 (0.82) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL25074609 0.83 HTR6 (0.73) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL25074608 0.82 HTR6 (0.71) HTR6HTR2AHTR2CHTR2BHTR1A
SCHEMBL3183303 0.82 HTR6 (0.71) HTR6HTR2AHTR2CHTR2BHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 US disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR6 12/4885HTR2A 5/4885HTR2C 4/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR6 549/4885HTR2A 377/4885HTR2C 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.