Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.71 |
| ▸ | HTR2A | P28223 | 11/20 | 0.66 |
| ▸ | HTR2C | P28335 | 6/20 | 0.66 |
| ▸ | HTR2B | P41595 | 6/20 | 0.66 |
| ▸ | HTR1A | P08908 | 6/20 | 0.66 |
| ▸ | HTR1B | P28222 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR5A | P47898 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25074609 | 0.85 | HTR6 (0.73) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL29758535 | 0.83 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL29993252 | 0.83 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL19235737 | 0.83 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL4208783 | 0.82 | HTR6 (0.97) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL26965639 | 0.82 | HTR6 (0.77) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL29168531 | 0.82 | HTR6 (0.71) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL26323272 | 0.82 | HTR6 (0.71) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL22800104 | 0.82 | HTR6 (0.71) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL4225666 | 0.81 | HTR6 (0.70) | HTR6HTR2AHTR2CHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260090957-A1 | Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness | DRESDNER JR KARL P (US) | 2026-04-02 | — | — | US | claimed |
| WO-2024254645-A1 | COMPOSITION AND METHOD TO TREAT, AMELIORATE OR PREVENT A PSYCHOLOGICAL, NEUROLOGICAL OR INFLAMMATORY DISORDER, AND METHOD FOR PREPARING COMPOSITION | Psychae Therapeutics Pty Ltd (AU) | 2024-12-19 | — | — | WO | claimed |
| WO-2024097868-A1 | STRUCTURE-ACTIVITY RELATIONSHIPS FOR PSILOCYBIN, BAEOCYSTIN, AERUGINASCIN, AND RELATED ANALOGUES TO PRODUCE PHARMACOLOGICAL EFFECTS | CAAMTECH, INC. (US) | 2024-05-10 | — | — | WO | claimed |
| US-11723894-B2 | Combination product for the treatment of neurological and/or psychiatric disorders | TERRAN BIOSCIENCES, INC. (US) | 2023-08-15 | — | — | US | claimed |
| US-20260137652-A1 | Composition Comprising Non-Phosphorylated Tryptamine | SINTALICA S R L (IT) | 2026-05-21 | — | — | US | disclosed |
| US-12622940-B2 | Combined fungal composition for modulating an inflammatory response | TURTLE BEAR HOLDINGS, LLC (US) | 2026-05-12 | — | — | US | disclosed |
| US-12622938-B2 | Compositions and methods for modulating inflammatory response | TURTLE BEAR HOLDINGS, LLC (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260108493-A1 | COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND | CAAMTECH, INC. (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260108544-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | TURTLE BEAR HOLDINGS LLC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12606543-B2 | Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto | MINDSET PHARMA INC. (CA) | 2026-04-21 | — | — | US | disclosed |
| US-20260102416-A1 | COMPOSITION OF MATTER FOR TREATING AT A MEDICAL CONDITION AND METHODS OF USE AND MANUFACTURE THEREOF | TLCO HOLDINGS INC. (US) | 2026-04-16 | — | — | US | disclosed |
| US-20260098286-A1 | Low Dose Psilocybin in Foodstuff and Microbes for Same | ATX PHARMERS LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-20180021326-A1 | Compositions and methods for enhancing neuroregeneration and cognition by combining mushroom extracts containing active ingredients psilocin or psilocybin with erinacines or hericenones enhanced with niacin | TURTLE BEAR HOLDINGS, LLC | 2018-01-25 | — | — | US | disclosed |
| US-8071786-B2 | Indole compounds useful as serotonin selective agents | GALENEA CORP. (US) | 2011-12-06 | — | — | US | disclosed |
| EP-2254865-A1 | INDOLE COMPOUNDS AND METHODS OF USE THEREOF | ORGANIX, INC. (US) | 2010-12-01 | — | — | EP | disclosed |
| US-20100137616-A1 | INDOLE COMPOUNDS USEFUL AS SEROTONIN SELECTIVE AGENTS | SARD HOWARD P | 2010-06-03 | — | — | US | disclosed |
| US-7655691-B2 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. | 2010-02-02 | — | — | US | disclosed |
| US-20090318527-A1 | INDOLE COMPOUNDS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-24 | — | — | US | disclosed |
| WO-2009102805-A1 | INDOLE COMPOUNDS AND METHODS OF USE THEREOF | ORGANIX INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20060100266-A1 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. (US) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622940-B2 | Combined fungal composition for modulating an inflammatory response | SORD, ERG28, IL1B | HTR6 3987/4885HTR2A 3723/4885HTR2C 3104/4885 |
| US-20090318527-A1 | INDOLE COMPOUNDS AND METHODS OF USE THEREOF | IDO1, IDO2, INMT | HTR6 8/4885HTR2A 27/4885HTR2C 30/4885 |
| US-20100137616-A1 | INDOLE COMPOUNDS USEFUL AS SEROTONIN SELECTIVE AGENTS | TPH1, TPH2, AANAT | HTR6 4/4885HTR2A 11/4885HTR2C 15/4885 |
| US-12622938-B2 | Compositions and methods for modulating inflammatory response | IL1B, IL1R1, ERG28 | HTR6 2601/4885HTR2A 3228/4885HTR2C 2332/4885 |
| US-20260098286-A1 | Low Dose Psilocybin in Foodstuff and Microbes for Same | PNMT, MYCBP, TPH1 | HTR6 5/4885HTR2A 6/4885HTR2C 8/4885 |
| US-20260102416-A1 | COMPOSITION OF MATTER FOR TREATING AT A MEDICAL CONDITION AND METHODS OF USE AND MANUFACTURE THEREOF | PDE8B, MGLL, PDE3B | HTR6 89/4885HTR2A 52/4885HTR2C 27/4885 |
| US-20260108493-A1 | COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND | ADRA2C, ADRB3, ADRA2B | HTR6 16/4885HTR2A 19/4885HTR2C 12/4885 |
| US-20260137652-A1 | Composition Comprising Non-Phosphorylated Tryptamine | HTR2B, BDNF, HTR3B | HTR6 30/4885HTR2A 31/4885HTR2C 17/4885 |
| US-20260090957-A1 | Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness | QPCT, SLC38A7, QPCTL | HTR6 2030/4885HTR2A 2610/4885HTR2C 1076/4885 |
| US-11723894-B2 | Combination product for the treatment of neurological and/or psychiatric disorders | HTR2A, HTR2C, HTR1A | HTR6 7/4885HTR2A 1/4885HTR2C 2/4885 |
| US-20180021326-A1 | Compositions and methods for enhancing neuroregeneration and cognition by combining mushroom extracts containing active ingredients psilocin or psilocybin with erinacines or hericenones enhanced with niacin | NES, PNMT, NGF | HTR6 182/4885HTR2A 112/4885HTR2C 199/4885 |
| US-20060100266-A1 | Indole compounds useful as serotonin selective agents | TPH1, TPH2, AANAT | HTR6 4/4885HTR2A 11/4885HTR2C 15/4885 |
| US-12606543-B2 | Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto | HTR6, CNR1, HTR3C | HTR6 1/4885HTR2A 15/4885HTR2C 4/4885 |
| US-20260108544-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | HTR1B, HTR6, BDNF | HTR6 2/4885HTR2A 9/4885HTR2C 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.