SCHEMBL26965698

SCHEMBL26965698

Cn1cc(CCCN)c2c(O)cccc21

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 13/20 0.65
HTR2A P28223 12/20 0.65
HTR2B P41595 8/20 0.65
HTR1A P08908 1/20 0.39
HTR1D P28221 1/20 0.39
GPR84 Q9NQS5 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTGS2 P35354 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26965630 0.91 HTR2C (0.68) HTR2CHTR2AHTR2BHTR1AHTR1D
SCHEMBL26965708 0.84 HTR2A (0.49) HTR2CHTR2AHTR2BTAAR1KDM4E
SCHEMBL26965676 0.82 HTR2A (0.62) HTR2CHTR2AHTR2BGPR84KDM4E
SCHEMBL26965706 0.82 HTR2C (0.67) HTR2CHTR2AHTR2BHTR1ATAAR1
SCHEMBL12558828 0.79 HTR2C (1.00) HTR2CHTR2AHTR2BHTR1AHTR1D
SCHEMBL26965705 0.79 HTR2A (0.65) HTR2CHTR2AHTR2BGPR84TAAR1
SCHEMBL2927520 0.79 HTR2A (0.65) HTR2CHTR2AHTR2BGPR84PTGS2
SCHEMBL29511842 0.79 HTR2C (1.00) HTR2CHTR2AHTR2BHTR1AHTR1D
SCHEMBL20119869 0.78 HTR2C (0.63) HTR2CHTR2AHTR2BKDM4E
SCHEMBL27542807 0.78 HTR2C (0.67) HTR2CHTR2AHTR2BGPR84PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 US disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR2C 4/4885HTR2A 5/4885HTR2B 2/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR2C 1196/4885HTR2A 377/4885HTR2B 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.