Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18860995 | 0.78 | ALDH1A1 (0.42) | TSHRP4HTMFFAR1ALDH1A1KDM4E | |
| SCHEMBL241757 | 0.76 | ALDH1A1 (0.48) | P4HTMFFAR1ALDH1A1KEAP1NPSR1 | |
| SCHEMBL2886185 | 0.75 | RAB9A (0.36) | TSHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3515895 | 0.75 | FFAR1 (0.55) | TSHRP4HTMFFAR1FFAR4ALDH1A1 | |
| SCHEMBL21293608 | 0.74 | CYP1A2 (0.47) | TSHRALDH1A1KDM4EMAPTHPGD | |
| Hydrochloric Acid SCHEMBL22775406 | 0.74 | ALDH1A1 (0.47) | P4HTMFFAR1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL17866361 | 0.74 | KEAP1 (0.41) | P4HTMFFAR1ALDH1A1KEAP1NPSR1 | |
| SCHEMBL15773979 | 0.73 | NPSR1 (0.44) | TSHRP4HTMFFAR1FFAR4ALDH1A1 | |
| SCHEMBL15265551 | 0.73 | KDM4E (0.35) | ALDH1A1KDM4E | |
| SCHEMBL26970722 | 0.71 | KDM4E (0.39) | TSHRFFAR1ALDH1A1KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416281-A1 | METHOD FOR PRODUCING (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID DERIVATIVE | KANEKA CORPORATION (JP) | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416281-A1 | METHOD FOR PRODUCING (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID DERIVATIVE | DPYD, BPGM, TPMT | TSHR 2692/4885P4HTM 3289/4885FFAR1 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.