Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27246864 | 0.85 | EDNRB (0.39) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3772018 | 0.84 | SMN1; SMN2 (0.42) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1087387 | 0.79 | MAPT (0.40) | MAPTRECQLALDH1A1KMT2ABMP1 | |
| SCHEMBL3760673 | 0.79 | MEN1 (0.33) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL5788622 | 0.78 | CA12 (0.36) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL16388122 | 0.78 | MEN1 (0.48) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL20570168 | 0.77 | CA12 (0.33) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL25318427 | 0.76 | KEAP1 (0.44) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL18977857 | 0.76 | KMT2A (0.40) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL34469410 | 0.75 | SMN1; SMN2 (0.38) | LMNAALDH1A1MEN1KMT2ABMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858918-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858918-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | LMNA 3309/4885MAPT 3314/4885RECQL 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.