Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772018 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL26970922 | 0.79 | LMNA (0.44) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL27246864 | 0.76 | EDNRB (0.39) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL5788622 | 0.76 | CA12 (0.36) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL21329586 | 0.75 | MEN1 (0.39) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL21330105 | 0.75 | MEN1 (0.39) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL21329582 | 0.75 | MEN1 (0.39) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL18029887 | 0.75 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL157669 | 0.75 | STAT3 (0.33) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL15237657 | 0.75 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846956-B2 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-07 | — | — | US | disclosed |
| US-7846956-B2 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20090149425-A1 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149425-A1 | Malononitrile compound as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1704143-B1 | MALONONITRILE COMPOUND AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149425-A1 | Malononitrile compound as pesticides | NR0B1, RTN4, OR10J3 | MEN1 929/4885KMT2A 3120/4885ALDH1A1 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.