Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20279926 | 0.70 | HTR3E (0.43) | PRKCBOPRM1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL8324812 | 0.64 | OPRM1 (0.63) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL25552047 | 0.62 | HSD11B1 (0.30) | — | |
| SCHEMBL15765668 | 0.62 | OPRM1 (0.63) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL13012389 | 0.62 | OPRM1 (0.63) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL12104025 | 0.62 | OPRM1 (0.63) | OPRM1LMNA | |
| SCHEMBL20280172 | 0.61 | OPRM1 (0.45) | PRKCBOPRM1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL31446066 | 0.61 | KMT2A (0.37) | FLT4LMNA | |
| SCHEMBL21392029 | 0.59 | OPRM1 (0.41) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL15733769 | 0.59 | OPRD1 (0.63) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858916-B2 | GLP-1 receptor agonists and uses thereof | PFIZER INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858916-B2 | GLP-1 receptor agonists and uses thereof | GLP1R, GIPR, GCGR | PRKCB 1109/4885OPRM1 1085/4885SLC22A1 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.