SCHEMBL26985266

SCHEMBL26985266

CC(C)(C)OC(=O)N1CCCC1c1ccc(Br)c(F)c1F

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 2/20 0.49
LMNA P02545 3/20 0.43
TSHR P16473 2/20 0.43
NR1H2 P55055 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 2/20 0.42
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
RIPK1 Q13546 2/20 0.41
KMT2A Q03164 2/20 0.41
USP30 Q70CQ3 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4564195 0.88 RIPK1 (0.48) UCHL1LMNATSHRNPC1ALDH1A1
SCHEMBL29747367 0.84 UCHL1 (0.48) UCHL1LMNATSHRNR1H2NPC1
SCHEMBL16881401 0.83 ALDH1A1 (0.44) UCHL1LMNATSHRNPC1ALDH1A1
SCHEMBL26985093 0.83 TSHR (0.42) UCHL1LMNATSHRNPC1ALDH1A1
SCHEMBL30679850 0.82 ALOX5AP (0.45) UCHL1LMNATSHRNPC1ALDH1A1
SCHEMBL31290628 0.82 USP30 (0.47) UCHL1LMNATSHRNR1H2NPC1
SCHEMBL26987927 0.82 USP30 (0.47) UCHL1LMNATSHRNR1H2NPC1
SCHEMBL31226409 0.82 ALOX5AP (0.45) UCHL1LMNATSHRNPC1ALDH1A1
SCHEMBL31226469 0.82 ALOX5AP (0.45) UCHL1LMNATSHRNPC1ALDH1A1
SCHEMBL3312132 0.81 NR1H2 (0.57) UCHL1LMNATSHRNR1H2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-09-02 US disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-24 US disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed
WO-2024010761-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed
WO-2024010761-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 UCHL1 3900/4885LMNA 1484/4885TSHR 3934/4885
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 UCHL1 3900/4885LMNA 1484/4885TSHR 3934/4885
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 UCHL1 3900/4885LMNA 1484/4885TSHR 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.