Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26989620 | 0.87 | HTR1D (0.59) | HTR2AMTNR1AMTNR1BHTR1AHTR1D | |
| SCHEMBL21693925 | 0.80 | HTR1A (0.65) | HTR2AHTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL26989647 | 0.78 | MTNR1A (0.55) | MTNR1AMTNR1BHTR1A | |
| SCHEMBL21709289 | 0.78 | MTNR1A (0.74) | MTNR1AMTNR1BHTR1A | |
| SCHEMBL26989667 | 0.77 | CA12 (0.34) | HTR2AMTNR1AMTNR1BDRD2HTR7 | |
| SCHEMBL26989142 | 0.76 | MTNR1A (0.60) | HTR2AMTNR1AMTNR1BHTR1AHTR1D | |
| SCHEMBL10567434 | 0.76 | HTR1D (0.49) | HTR2AMTNR1AMTNR1BHTR1AHTR1D | |
| SCHEMBL25057132 | 0.75 | HTR2C (0.68) | HTR2AHTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL29206374 | 0.75 | MPO (0.73) | HTR2AMTNR1AMTNR1BHTR1A | |
| SCHEMBL26989577 | 0.75 | HTR2A (0.68) | HTR2AHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008341-A1 | SEROTONIN ANALOGUES FOR USE IN TREATING METALLOPTOSIS-ASSOCIATED DISORDERS | INSTITUT CURIE (FR) | 2024-01-11 | — | — | WO | disclosed |