Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240058 | 0.85 | RXRA (0.58) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL5503219 | 0.85 | ALOX5 (0.51) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19612330 | 0.83 | ALOX5 (0.61) | L3MBTL1NPC1RAB9AALOX5TDP1 | |
| SCHEMBL19612293 | 0.81 | ALOX5 (0.46) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8859833 | 0.81 | NPC1 (0.62) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6237295 | 0.80 | MAPT (0.54) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5249927 | 0.80 | CYP2A6 (0.50) | L3MBTL1RAB9AALOX5CYP1A2CYP2A6 | |
| SCHEMBL12303122 | 0.80 | MAPT (0.54) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29097577 | 0.79 | RAB9A (0.49) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2383306 | 0.79 | MAOB (0.52) | L3MBTL1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010732-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINE TRANSPORTER ASCT2 AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-01-11 | — | — | WO | disclosed |