Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240058 | 0.87 | RXRA (0.58) | MAPTRAB9ALMNAHPGDMEN1 | |
| SCHEMBL30929949 | 0.81 | MAPT (0.55) | MAPTRAB9ALMNAL3MBTL1MEN1 | |
| SCHEMBL26993299 | 0.80 | L3MBTL1 (0.49) | MAPTRAB9ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9268448 | 0.76 | NPC1 (0.71) | MAPTRAB9ALMNAHPGDMEN1 | |
| SCHEMBL23461026 | 0.76 | CXCR2 (0.48) | MAPTRAB9ALMNAL3MBTL1HPGD | |
| SCHEMBL25548866 | 0.76 | PTPN1 (0.50) | LMNAHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23461024 | 0.76 | CXCR2 (0.48) | MAPTRAB9ALMNAL3MBTL1HPGD | |
| SCHEMBL15703639 | 0.75 | MAPT (0.62) | MAPTRAB9ALMNAL3MBTL1HPGD | |
| SCHEMBL8406035 | 0.74 | MAPT (0.57) | MAPTRAB9ALMNAL3MBTL1HPGD | |
| SCHEMBL8406034 | 0.74 | PTGER4 (0.59) | MAPTRAB9ALMNAL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |