Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22358029 | 0.74 | — | — | |
| SCHEMBL10123639 | 0.72 | KIF11 (0.35) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL17811228 | 0.68 | ALDH1A1 (0.31) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL21568795 | 0.68 | LRRK2 (0.34) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL12872400 | 0.65 | ALOX15 (0.44) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL22278022 | 0.65 | POLB (0.31) | GAAMAPT | |
| SCHEMBL17811230 | 0.65 | — | — | |
| SCHEMBL21691223 | 0.64 | ALDH1A1 (0.46) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL26997353 | 0.64 | KDM4E (0.35) | ALDH1A1MAPT | |
| SCHEMBL797357 | 0.63 | SSTR4 (0.48) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ALDH1A1 656/4885HPGD 565/4885ALOX15 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.