SCHEMBL2700543

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2700542	1.00	CYP1A2 (0.54)	CYP1A2HAO1CES2CES1CA1
	SCHEMBL2697770	0.83	MAPT (0.50)	CES2CES1CA2RXRARXRB
	SCHEMBL2697768	0.83	MAPT (0.50)	CES2CES1CA2RXRARXRB
	SCHEMBL2697875	0.83	ALDH1A1 (0.44)	CYP1A2CES2CES1CA1CA2
	SCHEMBL2697879	0.83	ALDH1A1 (0.44)	CYP1A2CES2CES1CA1CA2
	SCHEMBL2698488	0.83	NR4A1 (0.50)	CES2CES1RXRARXRBRXRG
	SCHEMBL2700540	0.83	MAPT (0.50)	CES2CES1CA2RXRARXRB
	SCHEMBL2698489	0.83	NR4A1 (0.50)	CES2CES1RXRARXRBRXRG
	SCHEMBL2698824	0.81	RXRA (0.45)	RXRARXRBRXRGALDH1A1HDAC1
	SCHEMBL2698826	0.81	RXRA (0.45)	RXRARXRBRXRGALDH1A1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.