Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27010379 | 0.94 | L3MBTL1 (0.48) | L3MBTL1TSHRCYP3A4CYP2D6MAPT | |
| SCHEMBL27010316 | 0.91 | L3MBTL1 (0.51) | L3MBTL1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL27010257 | 0.88 | ALDH1A1 (0.52) | TSHRCYP3A4CYP2D6ALDH1A1LMNA | |
| SCHEMBL27010245 | 0.88 | L3MBTL1 (0.50) | L3MBTL1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL24315784 | 0.87 | TSHR (0.47) | L3MBTL1TSHRCYP3A4CYP2D6MAPT | |
| SCHEMBL24317329 | 0.85 | TSHR (0.48) | L3MBTL1TSHRCYP3A4CYP2D6MAPT | |
| SCHEMBL26620049 | 0.85 | L3MBTL1 (0.49) | L3MBTL1TSHRCYP3A4CYP2D6MAPT | |
| SCHEMBL26620047 | 0.83 | TSHR (0.50) | L3MBTL1TSHRCYP3A4CYP2D6MAPT | |
| SCHEMBL26620048 | 0.83 | TSHR (0.52) | L3MBTL1TSHRCYP3A4CYP2D6MAPT | |
| SCHEMBL27010377 | 0.82 | L3MBTL1 (0.47) | L3MBTL1TSHRCYP2D6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | L3MBTL1 3664/4885TSHR 2445/4885CYP3A4 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.