Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620798 | 0.87 | ALDH1A1 (0.59) | KDM4EALDH1A1PKMIKZF2KDM1A | |
| SCHEMBL27010660 | 0.85 | HTT (0.42) | KDM4EPKMKDM1AMAOAMAOB | |
| SCHEMBL27010644 | 0.84 | IKZF2 (0.43) | IKZF2KDM1AMAOATACR1KMT2A | |
| SCHEMBL27010662 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1PKMKDM1AMAOA | |
| SCHEMBL27010700 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1PKMLMNATSHR | |
| SCHEMBL26620797 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1PKMKDM1AMAOA | |
| SCHEMBL27010641 | 0.77 | MAOA (0.47) | ALDH1A1KDM1AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL27010657 | 0.76 | ALDH1A1 (0.36) | KDM4EALDH1A1KDM1AMAOAMAOB | |
| SCHEMBL24315799 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1PKMLMNATSHR | |
| SCHEMBL8226104 | 0.72 | ALDH1A1 (0.97) | KDM4EALDH1A1PKMKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | KDM4E 791/4885ALDH1A1 2267/4885PKM 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.