Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.58 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.58 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564482 | 0.92 | BACE1 (0.57) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| Kushenol X SCHEMBL4809925 | 0.88 | BACE1 (0.72) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| SCHEMBL564492 | 0.87 | IDO1 (0.67) | ABCG2CACNA1HCACNA1GESR1IDO1 | |
| Kushenol N SCHEMBL27013513 | 0.84 | BACE1 (0.73) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| SCHEMBL564325 | 0.84 | BACE1 (0.80) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| Kushenol N SCHEMBL564568 | 0.84 | BACE1 (0.73) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| Kushenol N SCHEMBL564366 | 0.84 | BACE1 (0.73) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| SCHEMBL27013439 | 0.84 | BACE1 (0.80) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| Kushenol N SCHEMBL30451391 | 0.84 | BACE1 (0.73) | BACE1SLC5A1SLC5A2ABCG2CACNA1H | |
| Kushenol N SCHEMBL27013512 | 0.84 | BACE1 (0.73) | BACE1SLC5A1SLC5A2ABCG2CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | THPO, SERPINB1, SERPINC1 | BACE1 3298/4885SLC5A1 77/4885SLC5A2 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.