Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.57 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.57 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27013445 | 0.92 | BACE1 (0.58) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| Kushenol N SCHEMBL27013512 | 0.86 | BACE1 (0.73) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| Kushenol N SCHEMBL27013513 | 0.86 | BACE1 (0.73) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| Kushenol N SCHEMBL564366 | 0.86 | BACE1 (0.73) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| Kushenol N SCHEMBL30451391 | 0.86 | BACE1 (0.73) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| Kushenol N SCHEMBL564568 | 0.86 | BACE1 (0.73) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| Kushenol X SCHEMBL4809925 | 0.85 | BACE1 (0.72) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| SCHEMBL564492 | 0.79 | IDO1 (0.67) | ESR1CACNA1GCACNA1HABCG2IDO1 | |
| SCHEMBL564325 | 0.78 | BACE1 (0.80) | BACE1ACHESLC5A1SLC5A2PTGS1 | |
| SCHEMBL27013439 | 0.78 | BACE1 (0.80) | BACE1ACHESLC5A1SLC5A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1348762-A | Application of kusheng (sophora Flavescences) flavone in preparing hypoglycemic | LUZHOU BAOGUANG PHARMACEUTICAL (CN) | 2002-05-15 | — | — | CN | claimed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| US-10744219-B2 | Air freshener composition and preparation method thereof | Guorun Biotechnology (Shenzhen) Co., Ltd. (CN) | 2020-08-18 | — | — | US | disclosed |
| US-20200164096-A1 | AIR FRESHENER COMPOSITION AND PREPARATION METHOD THEREOF | Guorun Biotechnology (Shenzhen) Co., Ltd. (CN) | 2020-05-28 | — | — | US | disclosed |
| EP-3388137-B1 | AIR FRESHENER COMPOSITION AND PREPARATION METHOD THEREFOR | WANG JINGNING (CN) | 2020-04-15 | — | — | EP | disclosed |
| EP-3388137-A1 | AIR FRESHENER COMPOSITION AND PREPARATION METHOD THEREFOR | Wang, Jingning (CN) | 2018-10-17 | — | — | EP | disclosed |
| CN-102908341-A | Vitexicarpin used as pharmaceutical active ingredient with anti-angiogenesis function | UNIV TSINGHUA | 2013-02-06 | — | — | CN | disclosed |
| CN-102030812-B | Timosaponin A-III serving as medicinal active ingredient with angiogenesis resistance | UNIV TSINGHUA | 2012-07-04 | — | — | CN | disclosed |
| US-20120035855-A1 | METHOD OF NETWORK-BASED IDENTIFICATION FOR DRUG ACTION AND/OR SYNERGY EFFECT OF MEDICINE COMBINATION | TSINGHUA UNIVERSITY | 2012-02-09 | — | — | US | disclosed |
| EP-2369493-A1 | GENE NETWORK-BASED METHOD FOR CONFIRMING DRUG ACTION | Tsinghua University (CN) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010066150-A9 | GENE NETWORK-BASED METHOD FOR CONFIRMING DRUG ACTION | 清华大学 (CN) | 2011-07-21 | — | — | WO | disclosed |
| CN-102030812-A | Timosaponin A-III serving as medicinal active ingredient with angiogenesis resistance | UNIV TSINGHUA | 2011-04-27 | — | — | CN | disclosed |
| CN-102028679-A | Vitexin as active ingredient of medicine with anti-angiogenesis effect | UNIV TSINGHUA | 2011-04-27 | — | — | CN | disclosed |
| CN-1348762-A | Application of kusheng (sophora Flavescences) flavone in preparing hypoglycemic | LUZHOU BAOGUANG PHARMACEUTICAL (CN) | 2002-05-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | THPO, SERPINB1, SERPINC1 | BACE1 3298/4885ACHE 4241/4885SLC5A1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.