SCHEMBL27017289

SCHEMBL27017289

COC(=O)C[C@]1(C(=O)O)CC[C@@H](N)C1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
TP53 P04637 1/20 0.31
CYP2C19 P33261 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1543252 0.78 ARG1 (0.35) CYP1A2ARG1ARG2CYP2C19
SCHEMBL13010603 0.77 CYP2C19 (0.45) TP53CYP2C19
SCHEMBL9469790 0.71 CYP4F2 (0.37)
SCHEMBL9469793 0.71 CYP4F2 (0.37)
SCHEMBL6979479 0.70 CYP2C19 (0.33) CYP1A2CYP2C19
SCHEMBL27542500 0.69 CYP4F2 (0.42) ARG1ARG2EPHX2
Hydrochloric Acid SCHEMBL385319 0.68 GNAI3 (0.34) CYP2C19
Hydrochloric Acid SCHEMBL385321 0.68 GNAI3 (0.34) CYP2C19
Hydrochloric Acid SCHEMBL27539970 0.68 CYP4F2 (0.41) EPHX2
SCHEMBL31145967 0.65 CYP4F2 (0.47) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243187-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-07-31 US disclosed
EP-4551569-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2025-05-14 EP disclosed
CN-118159548-A Antiviral compounds 安力高医药股份有限公司 2024-06-07 CN disclosed
EP-4366831-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2024-05-15 EP disclosed
US-20240109871-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-04-04 US disclosed
US-20240018126-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-01-18 US disclosed
US-20240018126-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-01-18 US disclosed
US-20240018126-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-01-18 US disclosed
WO-2024010794-A1 ANTI-VIRAL COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2024-01-11 WO disclosed
US-11851422-B2 Anti-viral compounds ALIGOS THERAPEUTICS, INC. 2023-12-26 US disclosed
US-20230093249-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-03-23 US disclosed
WO-2023283256-A1 ANTI-VIRAL COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2023-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243187-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CYP1A2 3530/4885ARG1 1326/4885ARG2 1663/4885
US-20230093249-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CYP1A2 3530/4885ARG1 1326/4885ARG2 1663/4885
US-11851422-B2 Anti-viral compounds EIF2AK2, ZC3HAV1, HAVCR2 CYP1A2 3530/4885ARG1 1326/4885ARG2 1663/4885
US-20240018126-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CYP1A2 3530/4885ARG1 1326/4885ARG2 1663/4885
US-20240109871-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CYP1A2 3530/4885ARG1 1326/4885ARG2 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.