Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701439 | 0.84 | ABHD16A (0.49) | ABHD16AMGLLACHELMNABCHE | |
| SCHEMBL7048013 | 0.82 | ABHD16A (0.65) | ABHD16AMGLLLMNALIPCLIPE | |
| SCHEMBL2700152 | 0.82 | ABHD16A (0.69) | ABHD16AMGLLACHEBCHELIPC | |
| SCHEMBL2701503 | 0.81 | BCHE (0.42) | ABHD16AMGLLACHELMNABCHE | |
| SCHEMBL2701435 | 0.79 | NPC1 (0.46) | ABHD16AMGLLACHESMN1; SMN2TSHR | |
| SCHEMBL2700071 | 0.78 | MGLL (0.46) | ABHD16AMGLLACHEBCHELIPC | |
| SCHEMBL2701698 | 0.76 | MGLL (0.57) | ABHD16AMGLLACHELMNABCHE | |
| SCHEMBL2703046 | 0.76 | MGLL (0.57) | ABHD16AMGLLACHELMNABCHE | |
| SCHEMBL2701389 | 0.75 | MGLL (0.53) | ABHD16AMGLLACHEBCHELIPC | |
| SCHEMBL2701805 | 0.75 | MGLL (0.53) | ABHD16AMGLLACHEBCHELIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480960-B1 | Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, the production thereof and their use in medicaments | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-05-09 | — | — | EP | disclosed |
| US-6900233-B2 | Substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-05-31 | — | — | US | disclosed |
| EP-1480960-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXY-1,3,4-OXADIAZOL-2-ONES, THE PRODUCTION THEREOF AND THEIR USE IN MEDICAMENTS | Aventis Pharma Deutschland GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-20030181433-A1 | Substituted 3-phenyl-5-alkoxy-3H- (1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-09-25 | — | — | US | disclosed |
| WO-2003072555-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXY-1,3,4-OXADIAZOL-2-ONES, THE PRODUCTION THEREOF AND THEIR USE IN MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181433-A1 | Substituted 3-phenyl-5-alkoxy-3H- (1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof | PNLIP, LIPC, LPL | ABHD16A 103/4885MGLL 8/4885ACHE 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.