Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983658 | 0.85 | TSHR (0.32) | TSHRLMNATP53 | |
| SCHEMBL154543 | 0.83 | TP53 (0.37) | TSHRALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL2700599 | 0.80 | ALDH1A1 (0.34) | TSHRALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL4738020 | 0.80 | THRA (0.32) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2482070 | 0.79 | ESR1 (0.45) | TSHRALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL15648671 | 0.79 | BDKRB2 (0.36) | TSHRALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL15648819 | 0.79 | BDKRB2 (0.36) | TSHRALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL4556641 | 0.78 | ESR1 (0.55) | TSHRALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL7489132 | 0.78 | ALDH1A1 (0.61) | TSHRALDH1A1HSD17B10LMNAPTGS1 | |
| SCHEMBL2700589 | 0.78 | ENPP2 (0.38) | TSHRLPLLIPGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548269-B | Preparation method of diaryl methane structural compound | 兰州大学 | 2023-10-27 | — | — | CN | claimed |
| CN-111548269-A | Preparation method of diarylmethane structure compound | 兰州大学 | 2020-08-18 | — | — | CN | claimed |
| CN-111548269-B | Preparation method of diaryl methane structural compound | 兰州大学 | 2023-10-27 | — | — | CN | disclosed |
| WO-2020206381-A1 | CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS AND METHODS OF USING AND MAKING SAME | SUTTON LARRY D (US) | 2020-10-08 | — | — | WO | disclosed |
| CN-111548269-A | Preparation method of diarylmethane structure compound | 兰州大学 | 2020-08-18 | — | — | CN | disclosed |
| EP-2450354-B1 | LABELING COMPOUND FOR PET | RIKEN (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-20120230914-A1 | LABELING COMPOUND FOR PET | RIKEN (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2450354-A1 | LABELING COMPOUND FOR PET | Riken (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-5502065-A | TREATING HEADACHES | PFIZER INC. (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0636129-A1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS | Pfizer Limited (GB) | 1995-02-01 | — | — | EP | disclosed |
| CN-1082040-A | Indoles | PFIZER RES & DEV (IE) | 1994-02-16 | — | — | CN | disclosed |
| WO-1993021178-A1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS | PFIZER LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120230914-A1 | LABELING COMPOUND FOR PET | CYP19A1, CYP2F1, CYP4F11 | TSHR 315/4885ALDH1A1 1061/4885ESR1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.