Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL28963876 | 0.89 | GPR84 (0.49) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| Octadecanoic Acid Amide SCHEMBL27564226 | 0.84 | SOAT1 (0.55) | CA12CA2CA7CA9CA14 | |
| Octadecanoic Acid Amide SCHEMBL27614623 | 0.83 | SOAT1 (0.47) | CA12CA2CA7CA9CA14 | |
| Palmitamide SCHEMBL28694449 | 0.83 | SOAT1 (0.47) | CA12CA2CA7CA9CA14 | |
| SCHEMBL27990209 | 0.81 | ALDH1A1 (0.48) | CA12CA2CA7CA9CA14 | |
| SCHEMBL29001437 | 0.81 | CA2 (0.43) | CA12CA2CA7CA9CA14 | |
| SCHEMBL5446119 | 0.81 | TSHR (0.50) | CA12CA2CA7CA9CA14 | |
| Octadecanoic Acid Amide SCHEMBL368172 | 0.81 | SOAT1 (0.55) | SOAT1FAAHMEN1KMT2ATP53 | |
| Diethanolamine SCHEMBL6763687 | 0.81 | SOAT1 (0.55) | SOAT1FAAHMEN1KMT2ATP53 | |
| Diethanolamine SCHEMBL28070607 | 0.81 | SOAT1 (0.55) | SOAT1FAAHMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2449073-A1 | MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH AMINOSILICONE | The Procter & Gamble Company (US) | 2012-05-09 | — | — | EP | disclosed |
| US-7524809-B2 | Multiple use fabric conditioning composition with improved perfume | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-28 | — | — | US | disclosed |
| EP-1720967-A1 | MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH BLOOMING PERFUME | The Procter and Gamble Company (US) | 2006-11-15 | — | — | EP | disclosed |
| EP-1718719-A1 | MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH IMPROVED PERFUME | The Procter and Gamble Company (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005085404-A1 | MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH IMPROVED PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-15 | — | — | WO | disclosed |
| WO-2005085409-A1 | MULTIPLE USE FABRIC CONDITIONING COMPOSITION WITH BLOOMING PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050192204-A1 | Multiple use fabric conditioning composition with improved perfume | PROCTER & GAMBLE COMPANY, THE | 2005-09-01 | — | — | US | disclosed |
| US-20050192207-A1 | Multiple use fabric conditioning composition with blooming perfume | PROCTER & GAMBLE COMPANY, THE | 2005-09-01 | — | — | US | disclosed |