Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.49 |
| ▸ | FASN | P49327 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15361658 | 0.90 | CYP19A1 (0.59) | CYP19A1PTGS2PTGS1ALOX5PTGES | |
| SCHEMBL31545436 | 0.79 | MAOB (0.59) | CYP19A1PTGS2PTGS1ALOX5PTGES | |
| SCHEMBL31576819 | 0.79 | ALOX5 (0.76) | CYP19A1PTGS2PTGS1ALOX5PTGES | |
| SCHEMBL9578229 | 0.79 | ALOX5 (0.76) | CYP19A1PTGS2PTGS1ALOX5PTGES | |
| SCHEMBL7898977 | 0.78 | CYP19A1 (0.55) | CYP19A1PTGS2PTGS1ALOX5PTGES | |
| SCHEMBL5165075 | 0.76 | MEN1 (0.66) | ALOX5PTGESPTPN1HPGDMGAM | |
| SCHEMBL21807688 | 0.75 | CYP19A1 (0.58) | CYP19A1PTGS2ALOX5SMPD1NUDT1 | |
| SCHEMBL30100945 | 0.75 | PTGS1 (0.58) | CYP19A1PTGS2PTGS1ALOX5PTGES | |
| SCHEMBL5932059 | 0.74 | MAOB (0.62) | CYP19A1PTGS2PTGS1ALOX5SMPD1 | |
| SCHEMBL24075565 | 0.74 | FFAR1 (0.59) | CYP19A1PTGS2PTGS1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308262-A1 | PROCESS FOR PREPARING ABSOLUTES | International Flavors & Fragrances Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197576-A1 | PROCESS FOR PREPARING ABSOLUTES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-09-22 | — | — | WO | disclosed |