Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576819 | 0.85 | ALOX5 (0.76) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL9578229 | 0.85 | ALOX5 (0.76) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL16343640 | 0.84 | SMPD1 (0.60) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL30100963 | 0.84 | FFAR1 (0.64) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL15361077 | 0.82 | MAOB (0.49) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL24075565 | 0.80 | FFAR1 (0.59) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL31576809 | 0.80 | FFAR1 (0.59) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL24075664 | 0.80 | HIF1A (0.54) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL31576814 | 0.80 | HIF1A (0.54) | PTGS1ALOX5PTGS2PTGESSMPD1 | |
| SCHEMBL15361658 | 0.79 | CYP19A1 (0.59) | PTGS1ALOX5PTGS2PTGESSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262775-A1 | Methods to synthesize cyclopentenes and cyclopentadienes by ring contraction | NATURAL EXTRACTION SYS LLC (US) | 2024-08-08 | — | — | US | disclosed |
| WO-2022240895-A1 | METHODS TO SYNTHESIZE CYCLOPENTENES AND CYCLOPENTADIENES BY RING CONTRACTION | Natural Extraction Systems, LLC (US) | 2022-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262775-A1 | Methods to synthesize cyclopentenes and cyclopentadienes by ring contraction | PTGIS, CYC1, CYCS | PTGS1 10/4885ALOX5 76/4885PTGS2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.