Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.76 |
| ▸ | PTGES | O14684 | 1/20 | 0.76 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578229 | 1.00 | ALOX5 (0.76) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL29495886 | 0.87 | ALOX5 (1.00) | ALOX5PTGS2PTGS1PTGESPTPN1 | |
| SCHEMBL30100945 | 0.85 | PTGS1 (0.58) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL24075565 | 0.84 | FFAR1 (0.59) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL31576809 | 0.84 | FFAR1 (0.59) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL15361658 | 0.83 | CYP19A1 (0.59) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| Preremirol SCHEMBL24305165 | 0.83 | ALOX5 (0.65) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL1933140 | 0.83 | PTGES (0.58) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL24075657 | 0.82 | SMPD1 (0.60) | ALOX5PTGS2PTGS1PTGESSMPD1 | |
| SCHEMBL30100963 | 0.82 | FFAR1 (0.64) | ALOX5PTGS2PTGS1PTGESSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104281-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-05-22 | — | — | WO | disclosed |
| EP-4556004-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | Centre National de la Recherche Scientifique (FR) | 2025-05-21 | — | — | EP | disclosed |