Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705044 | 0.89 | AVPR2 (0.47) | ALDH1A1TSHRAVPR2POLBIDO1 | |
| SCHEMBL2933189 | 0.88 | AVPR2 (0.52) | ALDH1A1TSHRAVPR2POLBLMNA | |
| SCHEMBL2704087 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRAVPR2NPSR1LMNA | |
| SCHEMBL28501007 | 0.77 | MAPT (0.45) | ALDH1A1TSHRNPSR1POLBLMNA | |
| SCHEMBL2705045 | 0.74 | AVPR2 (0.47) | ALDH1A1TSHRAVPR2POLBLMNA | |
| SCHEMBL2933193 | 0.72 | AVPR2 (0.59) | ALDH1A1TSHRAVPR2POLBLMNA | |
| SCHEMBL2937767 | 0.71 | AVPR2 (0.64) | AVPR2 | |
| SCHEMBL2702924 | 0.71 | AVPR2 (0.51) | ALDH1A1TSHRAVPR2 | |
| SCHEMBL23142269 | 0.71 | KDM4E (0.45) | ALDH1A1TSHRNPSR1POLBLMNA | |
| SCHEMBL4894406 | 0.70 | SLC22A12 (0.49) | ALDH1A1TSHRPOLBLMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256119-B1 | Vasopressin V1a antagonists | VANTIA LTD (GB) | 2012-05-09 | — | — | EP | claimed |