Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171384 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL23142269 | 0.81 | KDM4E (0.45) | MAPTALDH1A1TSHRCREBBPKDM4E | |
| SCHEMBL10274848 | 0.79 | NOTUM (0.65) | MAPTALDH1A1CREBBPMEN1KMT2A | |
| SCHEMBL28560567 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL30096479 | 0.77 | AGTR2 (0.39) | MAPTNOTUMLMNA | |
| SCHEMBL2704086 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1TSHRCREBBPPOLB | |
| SCHEMBL13698998 | 0.76 | CYP11B1 (0.43) | MAPTALDH1A1TSHRPOLBKMT2A | |
| SCHEMBL11431097 | 0.76 | ALDH1A1 (0.59) | MAPTALDH1A1TSHRCREBBPMEN1 | |
| SCHEMBL11442963 | 0.75 | ALDH1A1 (0.37) | MAPTALDH1A1TSHRCREBBPMEN1 | |
| SCHEMBL2704087 | 0.75 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511220-B | P-diaminobenzene derivatives as potassium channel modulators, process for their preparation and their use in medicine | 上海挚盟医药科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-112119079-A | P-diaminobenzene derivatives as potassium channel modulators, process for their preparation and their use in medicine | 上海挚盟医药科技有限公司 | 2020-12-22 | — | — | CN | disclosed |