Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045984 | 0.90 | PTGS2 (0.56) | PTGS2PTGDR2XIAPADORA2AADORA1 | |
| SCHEMBL27045983 | 0.89 | PTGS2 (0.43) | PTGS2PTGDR2XIAPMAPTKDM4E | |
| SCHEMBL27045675 | 0.87 | PTGS2 (0.43) | PTGS2PTGDR2ATAD2XIAPADORA3 | |
| SCHEMBL27045441 | 0.87 | PTGS2 (0.47) | PTGS2PTGDR2ATAD2XIAPMAPT | |
| SCHEMBL27045994 | 0.85 | PTGS2 (0.42) | PTGS2ATAD2XIAPADORA3ADORA2A | |
| SCHEMBL27045811 | 0.82 | PTGS2 (0.46) | PTGS2PTGDR2ADORA3ADORA2AADORA1 | |
| SCHEMBL27045590 | 0.82 | PTGS2 (0.46) | PTGS2PTGDR2ATAD2XIAPADORA3 | |
| SCHEMBL27045683 | 0.81 | PTGS2 (0.45) | PTGS2PTGDR2ATAD2XIAPADORA3 | |
| SCHEMBL27046426 | 0.80 | ALDH1A1 (0.56) | PTGDR2XIAPMAPTKDM4EALDH1A1 | |
| SCHEMBL27045589 | 0.79 | ALDH1A1 (0.41) | PTGS2PTGDR2XIAPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |