Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045997 | 0.93 | PTGS2 (0.50) | PTGS2XIAPADORA2AADORA1ADORA3 | |
| SCHEMBL27045996 | 0.90 | PTGS2 (0.41) | PTGS2XIAPADORA2AADORA1KDM4E | |
| SCHEMBL27045841 | 0.88 | PTGS2 (0.39) | PTGS2ATAD2XIAPADORA2AADORA1 | |
| SCHEMBL27045580 | 0.85 | PTGS2 (0.46) | PTGS2ATAD2XIAPADORA2AADORA1 | |
| SCHEMBL27046353 | 0.84 | PTGS2 (0.42) | PTGS2ATAD2XIAPADORA2AADORA1 | |
| SCHEMBL27046002 | 0.84 | PTGS2 (0.42) | PTGS2ATAD2XIAPADORA2AADORA1 | |
| SCHEMBL27045441 | 0.83 | PTGS2 (0.47) | PTGS2ATAD2XIAPKDM4EALDH1A1 | |
| SCHEMBL27046116 | 0.82 | ATAD2 (0.39) | PTGS2ATAD2XIAPADORA2AADORA1 | |
| SCHEMBL27049052 | 0.82 | PTGS2 (0.51) | PTGS2XIAPADORA2AADORA1ADORA3 | |
| SCHEMBL27045989 | 0.81 | PTGS2 (0.41) | PTGS2ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |