Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 4/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045673 | 0.88 | CNR2 (0.35) | CNR2PTGS2MAPK14CTSLCTSB | |
| SCHEMBL27045440 | 0.88 | PTGS2 (0.41) | PTGS2MEN1KMT2AS1PR4S1PR5 | |
| SCHEMBL27045351 | 0.85 | HPGDS (0.35) | PTGS2S1PR4S1PR5HPGDSMCL1 | |
| SCHEMBL27045831 | 0.84 | MEN1 (0.37) | CNR2PTGS2MAPK14CTSLCTSB | |
| SCHEMBL27045680 | 0.84 | CNR2 (0.37) | CNR2PTGS2MAPK14CTSLCTSB | |
| SCHEMBL27045583 | 0.83 | MEN1 (0.36) | CNR2PTGS2MAPK14CTSLCTSB | |
| SCHEMBL27045234 | 0.82 | MEN1 (0.37) | CNR2PTGS2MAPK14MEN1POLB | |
| SCHEMBL27045984 | 0.81 | PTGS2 (0.56) | PTGS2MEN1KMT2APTGDR2XIAP | |
| SCHEMBL27045226 | 0.80 | ACHE (0.39) | CNR2PTGS2MEN1POLBKMT2A | |
| SCHEMBL27045983 | 0.77 | PTGS2 (0.43) | PTGS2MEN1KMT2APTGDR2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |