Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045835 | 0.89 | HPGDS (0.35) | HPGDSPARP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL27045833 | 0.86 | HPGDS (0.37) | HPGDSPARP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL27046350 | 0.86 | HPGDS (0.37) | HPGDSPARP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL27045982 | 0.85 | CNR2 (0.37) | HPGDSS1PR4S1PR5PTGS2ABL1 | |
| SCHEMBL27046113 | 0.84 | HPGDS (0.36) | HPGDSPARP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL27045440 | 0.84 | PTGS2 (0.41) | HPGDSS1PR4S1PR5PTGS2ABL1 | |
| SCHEMBL27045691 | 0.83 | ABL1 (0.34) | HPGDSPARP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL27045997 | 0.83 | PTGS2 (0.50) | ADORA2AADORA1PTGS2AAK1KDM4E | |
| SCHEMBL27045996 | 0.80 | PTGS2 (0.41) | ADORA2AADORA1PTGS2AAK1KDM4E | |
| SCHEMBL27045994 | 0.80 | PTGS2 (0.42) | ADORA2AADORA1PTGS2AAK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |