SCHEMBL2704646

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18910226	0.96	ADRB1 (0.48)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL23152941	0.96	MAPKAPK2 (0.50)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL17269404	0.94	HPGD (0.44)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL19601159	0.94	LMNA (0.43)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL4473427	0.94	ALDH1A1 (0.51)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL21477316	0.93	MAPKAPK2 (0.41)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL17269410	0.93	POLB (0.43)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL17269417	0.92	CHRNA10 (0.46)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL20988009	0.92	CHRNA10 (0.42)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2
	SCHEMBL18910121	0.91	ALDH1A1 (0.50)	ALDH1A1USP2TSHRHSD17B10MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.