Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | F11 | P03951 | 5/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27046584 | 0.76 | TPSAB1 (0.45) | F11TPSAB1TPSD1TPSG1FOLH1 | |
| SCHEMBL20302623 | 0.73 | ELANE (0.38) | ELANEF11TPSAB1TPSD1TPSG1 | |
| SCHEMBL18476312 | 0.72 | F11 (0.76) | ELANEF11TPSAB1TPSD1TPSG1 | |
| SCHEMBL21478292 | 0.72 | ELANE (0.38) | ELANEF11TPSAB1TPSD1TPSG1 | |
| SCHEMBL20302389 | 0.72 | F11 (0.57) | F11 | |
| SCHEMBL16997586 | 0.70 | F11 (0.57) | ELANEF11TPSAB1TPSD1TPSG1 | |
| SCHEMBL16997636 | 0.69 | F11 (0.68) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL27046465 | 0.67 | TPSAB1 (0.33) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL4751699 | 0.67 | F11 (0.62) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL16998455 | 0.66 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4309653-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | Exithera Pharmaceuticals Inc. (US) | 2024-01-24 | — | — | EP | disclosed |