SCHEMBL2704691

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2831462	0.91	NPC1 (0.77)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL30050253	0.89	RAB9A (0.66)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL28566662	0.89	RAB9A (0.66)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL19577671	0.89	NPC1 (0.70)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL10160169	0.89	HIF1A (0.74)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL4854629	0.89	NAMPT (0.76)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL25709720	0.86	MTOR (0.62)	MAPTNPC1RAB9ASMN1; SMN2MAOB
	SCHEMBL20804368	0.85	NPC1 (0.65)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL31401956	0.84	MAPT (0.57)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL14025738	0.84	NPC1 (0.73)	MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.